| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377662 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A novel triarylimidazole derivative, SB-590885 (33), bearing a 2,3-dihydro-1H-inden-1-one oxime substituent has been identified as a potent and extremely selective inhibitor of B-Raf kinase.
Graphical abstractA novel triarylimidazole derivative, SB-590885 (33), bearing a 2,3-dihydro-1H-inden-1-one oxime substituent has been identified as a potent and extremely selective inhibitor of B-Raf kinase.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Andrew K. Takle, Murray J.B. Brown, Susannah Davies, David K. Dean, Gerraint Francis, Alessandra Gaiba, Alex W. Hird, Frank D. King, Peter J. Lovell, Antoinette Naylor, Alastair D. Reith, Jon G. Steadman, David M. Wilson,