| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377694 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A new cyclic nonapeptide, segetalin F, has been isolated from the seeds of Vaccaria segetalis and the structure including absolute stereochemistry was elucidated by using 2D NMR and chemical means. A series of segetalins showed a vasorelaxant activity against norepinephrine (NE)-induced contractions of rat aorta.
Graphical abstractA new cyclic nonapeptide, segetalin F (6), has been isolated from the seeds of Vaccaria segetalis and the structure was elucidated by using 2D NMR and chemical means. A series of segetalins showed a vasorelaxant activity against norepinephrine (NE)-induced contractions of rat aorta.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Authors
Hiroshi Morita, Michiko Eda, Toru Iizuka, Yusuke Hirasawa, Mitsuhiro Sekiguchi, Young Sook Yun, Hideji Itokawa, Koichi Takeya,