Article ID Journal Published Year Pages File Type
1377719 Bioorganic & Medicinal Chemistry Letters 2006 5 Pages PDF
Abstract

A versatile method for novel pyrido-quinazolones was described here and tested for anti-fungal, antibacterial, and anticancerous activities. These synthesized compounds were characterized on the basis of spectroscopic techniques and evaluated for specific radiopharmaceuticals. Preliminary radiolabeling results with 99mTc and biological evaluation studies showed promising results for further evaluation in vivo. The efficiency of labeling was more than 98% and complexes were stable for about 18 h at 25 °C in the presence of serum.

Graphical abstractA versatile method for novel pyrido-quinazolone analogues as anti-fungal, antibacterial, and anticancer agents is described here. These synthesized compounds were characterized on the basis of spectroscopic techniques and evaluated for specific radiopharmaceuticals.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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