| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377744 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
Synthesis of C12 des-methyl ketolides is developed featuring an intramolecular epoxide formation/elimination process to establish the C12 stereocenter. These ketolides are potent against several key respiratory pathogens including resistant strains.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaodong Lin, Alice C. Rico, Daniel T. Chu, Georgia L. Carroll, Lynn Barker, Ribhi Shawar, Manoj C. Desai, Jacob J. Plattner,