Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1377775 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Unprecedented classes of four- and five-membered hydroxyl-spiro-β-lactams and hydroxyl-azido-β-lactams were prepared via regioselective ring opening of hydroxyl-epoxides. The potential of these particular β-lactams as biologically active compounds has been confirmed by the results obtained in ACAT inhibition assays.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Fides Benfatti, Giuliana Cardillo, Luca Gentilucci, Alessandra Tolomelli,