| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377820 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
Sequential, position-selective, Pd-catalyzed cross-coupling reactions of 2,4-dibromo-5-hydroxymethylthiazole provided the scaffold for the synthesis of GW501516, the most potent PPARβ/δ agonist yet described, and equally selective analogs at the thiazole-C4 position.
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Related Topics
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Authors
Raquel Pereira, Claudine Gaudon, Beatriz Iglesias, Pierre Germain, Hinrich Gronemeyer, Angel R. de Lera,