| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377826 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
High-throughput screening revealed compound 1 as a potent antagonist of the CCK1 receptor. Here, we disclose the synthesis of combinatorial libraries by solid-phase synthesis on Kenner 'safety catch' resin. Additive QSAR models were used to determine a lack of consistent additive SAR within the matrix.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Clark Sehon, Kelly McClure, Michael Hack, Magda Morton, Laurent Gomez, Lina Li, Terrance D. Barrett, Nigel Shankley, J. Guy Breitenbucher,