| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377837 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
The discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-(S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of dipeptidyl peptidase IV (DPP IV) are reported.
Graphical abstractThe discovery, SAR, and X-ray crystal structure of novel biarylaminoacyl-(S)-2-cyano-pyrrolidines and biarylaminoacylthiazolidines as potent inhibitors of dipeptidyl peptidase IV (DPP IV) are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lei Qiao, Christian A. Baumann, Carl S. Crysler, Nisha S. Ninan, Marta C. Abad, John C. Spurlino, Renee L. DesJarlais, Jukka Kervinen, Mike P. Neeper, Shariff S. Bayoumy, Robyn Williams, Ingrid C. Deckman, Malini Dasgupta, Rolanda L. Reed,