| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377928 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
A series of 2-pyridinylpiperazines derived from β-Ala-(2,4-Cl)Phe dipeptide was synthesized for the study of their SARs and possible interactions with the MC4 receptor. Compounds such as 11k (Ki = 6.5 nM) possessed high potency.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Joe A. Tran, Joseph Pontillo, Beth A. Fleck, Dragan Marinkovic, Melissa Arellano, Fabio C. Tucci, Marion Lanier, John Saunders, Wanlong Jiang, Caroline W. Chen, Alan C. Foster, Chen Chen,