| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377965 | Bioorganic & Medicinal Chemistry Letters | 2006 | 4 Pages |
Abstract
The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with IR, UV–vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms.
Graphical abstractThe synthesis, spectroscopic study, crystal structure, and biological activity of the mononuclear Cu(II) complex with the third-generation quinolone sparfloxacin are reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Eleni K. Efthimiadou, Yiannis Sanakis, Catherine P. Raptopoulou, Alexandra Karaliota, Nikos Katsaros, George Psomas,