| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1377996 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
A new class of bicyclic pyrrolopyrimidine-based Janus kinase 3 (JAK-3) inhibitors are described. Many of these inhibitors showed low nanomolar activity against JAK-3.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michael P. Clark, Kelly M. George, Roger G. Bookland, Jack Chen, Steven K. Laughlin, Kumar D. Thakur, Wenlin Lee, Jan R. Davis, Ed J. Cabrera, Todd A. Brugel, John C. VanRens, Matthew J. Laufersweiler, Jennifer A. Maier, Mark P. Sabat, Adam Golebiowski,