| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378003 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
A novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiazolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDAMB468 cancer cells.
Graphical abstractA novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiaszolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDA MB468 cancer cells.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jinho Lee, Taesik Park, Shinwu Jeong, Kyoung-Hee Kim, Changyong Hong,