| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378014 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
The synthesis of new conformationally biased cyclic pentapeptides, incorporating the RGD sequence, and built around a tetrahydroazoninone scaffold, is reported. They exhibit interesting activity towards integrin αVβ3 and a remarkable selectivity in comparison with integrin αVβ5.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Luca Banfi, Andrea Basso, Gianluca Damonte, Federico De Pellegrini, Andrea Galatini, Giuseppe Guanti, Ilaria Monfardini, Renata Riva, Carlo Scapolla,