| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378024 | Bioorganic & Medicinal Chemistry Letters | 2007 | 7 Pages |
Abstract
A 1,6-naphthyridine inhibitor of HIV-1 integrase has been discovered with excellent inhibitory activity in cells, good pharmacokinetics, and an excellent ability to inhibit virus with mutant enzyme.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Melissa S. Egbertson, H. Marie Moritz, Jeffrey Y. Melamed, Wei Han, Debra S. Perlow, Michelle S. Kuo, Mark Embrey, Joseph P. Vacca, Matthew M. Zrada, Amanda R. Cortes, Audrey Wallace, Yvonne Leonard, Daria J. Hazuda, Michael D. Miller, Peter J. Felock,