| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378139 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The solid-phase synthesis of a library based on the natural product anisomycin is described. The resulting library was tested against a panel of bacterial and fungal targets, and active compounds were identified in a Staphylococcus aureus whole-cell assay and an efflux-deficient fungal whole-cell assay.
Graphical abstractSolid-phase synthesis of a library based on the natural product anisomycin is described. The resulting library was tested against a panel of bacterial and fungal targets, and active compounds were identified in a Staphylococcus aureus whole-cell assay and an efflux-deficient fungal whole-cell assay.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shuhao Shi, Shirong Zhu, Samuel W. Gerritz, Kim Esposito, Ramesh Padmanabha, Wenying Li, John J. Herbst, Henry Wong, Yue Zhong Shu, Kin S. Lam, Michael J. Sofia,