| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378222 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
A series of novel xanthenone aminoderivatives and their pyrazole-fused counterparts possessing structural analogy to the potent anticancer agent 9-methoxypyrazoloacridine (PZA) reported. These compounds exhibited an interesting cytotoxic activity against a panel of cell lines. Most noticeably, they retain activity against the multidrug resistant MES-SA/Dx5 subline, showing resistant factors close to 1.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ioannis K. Kostakis, Roxane Tenta, Nicole Pouli, Panagiotis Marakos, Alexios-Leandros Skaltsounis, Harris Pratsinis, Dimitris Kletsas,