Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378265 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
A series of 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives were synthesized and evaluated for in vitro activity against the endoparasite Haemonchus contortus and the ectoparasite Ctenocephalides felis. Some compounds had significant in vitro activity against these parasites.
Graphical abstractWe describe the synthesis of a set of (Z)-2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives and the in vitro screening of these compounds against the animal parasites Haemonchus contortus and Ctenocephalides felis.Figure optionsDownload full-size imageDownload as PowerPoint slide
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Abdelselam Ali, Marianne Bliese, Jo-Anne M. Rasmussen, Roger M. Sargent, Simon Saubern, David G. Sawutz, John S. Wilkie, David A. Winkler, Kevin N. Winzenberg, Ruth C.J. Woodgate,