| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378267 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Eight monosaccharide analogs of the potent antitumor OSW saponins (2–9) were synthesized. One analog, 2-O-acetyl-α-l-arabinopyranoside 3, showed antiproliferative activity against the Jurkat cells (IC50 = 0.078 μM) comparable to that of the disaccharide derivative (1).
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Pingping Tang, Fatemah Mamdani, Xiaoyi Hu, Jun O. Liu, Biao Yu,