| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378352 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Four carbon-11-labeled camptothecin derivatives, 9-[11C]methoxy-20(S)-camptothecin ([11C]5), 10-[11C]methoxy-20(S)-camptothecin ([11C]7), 9-nitro-10-[11C]methoxy-20(S)-camptothecin ([11C]9), and 9-[([11C]trimethylamino)methyl]-10-hydroxy-20(S)-camptothecin ([11C]11), have been synthesized as potential positron emission tomography tracers for imaging of topoisomerase I in cancers.
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Related Topics
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Authors
Mingzhang Gao, Kathy D. Miller, George W. Sledge, Qi-Huang Zheng,