Article ID Journal Published Year Pages File Type
1378354 Bioorganic & Medicinal Chemistry Letters 2005 7 Pages PDF
Abstract
The rigid nicotine analog ACME and its N-cyanoborane conjugate ACME-B are selective partial agonists of rat α7 nicotinic receptors expressed in Xenopus oocytes, with no significant activation of either α3β4 or α4β2 receptors. ACME-B is both more potent and efficacious than ACME.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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