| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378361 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
An optimized side chain for dihydrobenzoxathiin SERAMs was discovered and attached to four dihydrobenzoxathiin platforms. The novel SERAMs show exceptional estrogen antagonist activity in uterine tissue and an MCF-7 breast cancer cell assay.
Graphical abstractAn optimized side chain for dihydrobenzoxathiin SERAMs was discovered and attached to four dihydrobenzoxathiin platforms. The novel SERAMs show exceptional estrogen antagonist activity in uterine tissue and an MCF-7 breast cancer cell assay.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Timothy A. Blizzard, Frank DiNinno, Helen Y. Chen, Seongkon Kim, Jane Y. Wu, Wanda Chan, Elizabeth T. Birzin, Yi Tien Yang, Lee-Yuh Pai, Edward C. Hayes, Carolyn A. DaSilva, Susan P. Rohrer, James M. Schaeffer, Milton L. Hammond,