| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378373 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
3-Pyridinylboronic acid is identified as a key sensing element for reversible sugar complexation in an aqueous solution at the physiological pH. The utility of a sensing element has been demonstrated through a simple colorimetric titration of glucose using absorption spectroscopy in the visible region. The mechanism of the high diol/triol binding affinity of pyridine boronic acid in the neutral pH is discussed based on the 1H and 11B NMR spectroscopic studies.
Graphical abstractThe unusually high binding affinity of 3-pyridinylboronic acid to sugars is reported.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Serhan Boduroglu, Jouliana M. El Khoury, D. Venkat Reddy, Peter L. Rinaldi, Jun Hu,