Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378471 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
A potential radiopharmaceutical and HSV1-TK substrate, 3-((1,3-dihydroxypropan-2-yloxy)-methyl)-6-(4-(3-((2-mercaptoethyl)(2-(2-mercaptoethyl-amino)-ethyl)amino)propoxy)phenyl)-3H-imidazopurin-9(5H)-one-oxo-technetium(V), was synthesized via a converging approach and its chemical structure was comparatively characterized with a non-radioactive analog. The final radiochemical purity and yield were 97 and 73%, respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yi Zhang, Jing Lin, Dongfeng Pan,