Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378484 | Bioorganic & Medicinal Chemistry Letters | 2007 | 4 Pages |
Abstract
C2R-Fluoro substituted DC-81 and its dimers have been synthesized that exhibit significant DNA-binding ability, particularly the five carbon alkane spacer compound (6c) showed the helix melting temperature (ΔTm) of 18.8 °C after incubation of 36 h at 37 °C.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ahmed Kamal, D. Rajasekhar Reddy, P.S. Murali Mohan Reddy,