| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378492 | Bioorganic & Medicinal Chemistry Letters | 2007 | 5 Pages |
Abstract
Several thiazolone-based sulfonamides were prepared, utilizing various hetero-aryl sulfonyl chlorides and different aldehydes, as inhibitors of NS5B polymerase, to target HCV. The best compound showed 0.6 nM of IC50 inhibitory activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yili Ding, Kenneth L. Smith, Chamakura V.N.S. Varaprasad, Eugene Chang, John Alexander, Nanhua Yao,