Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378507 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The enantiopure 2-(1,2,3,4-tetrahydro-1-isoquinolyl)ethanol derivatives 4 were evaluated for their affinity to the ifenprodil binding site of the NMDA receptor, their potency to inhibit [3H]MK801 binding, their NMDA-NR2B subtype selectivity and their affinity to HERG K+ channels.
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Authors
Georg Höfner, Cornelia E. Hoesl, Chris Parsons, Günther Quack, Klaus T. Wanner,