| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378537 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
A series of potent PDE5 inhibitors with high selectivity versus PDE6 isoenzymes was identified.
Graphical abstractA series of potent PDE5 inhibitors with high selectivity versus PDE6 was identified.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![New pyrazolo[1′,5′:1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors](/preview/png/1378537.png "First Page Preview: New pyrazolo[1′,5′:1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective PDE5 inhibitors")
Authors
Joan Feixas, Maria Paola Giovannoni, Claudia Vergelli, Amadeu Gavaldà, Nicoletta Cesari, Alessia Graziano, Vittorio Dal Piaz,