Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378563 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
The metabolic stability of benzoxazinone derivatives, a potent series of NPY5 antagonists, has been investigated. This study identified the moieties prone to metabolic transformation and provides the opportunity to optimize the structure of this new class of NPY5 antagonists.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alberto Dordal, Mike Lipkin, Jackie Macritchie, Josep Mas, Adriana Port, Sally Rose, Leonardo Salgado, Vladimir Savic, Wolfgang Schmidt, Maria Teresa Serafini, William Spearing, Antoni Torrens, Sandra Yeste,