| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378564 | Bioorganic & Medicinal Chemistry Letters | 2005 | 6 Pages |
Abstract
SAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing hormone receptor antagonists resulted in potent compounds. The best compound from the series had a binding affinity of 2 nM.
Graphical abstractSAR studies of 1,3,5-triazine-2,4,6-triones as human gonadotropin-releasing receptor antagonists resulted in potent compounds. The best compound from the series had a binding affinity of 2 nM.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Zhiqiang Guo, Dongpei Wu, Yun-Fei Zhu, Fabio C. Tucci, Collin F. Regan, Martin W. Rowbottom, R. Scott Struthers, Qiu Xie, Shelby Reijmers, Susan K. Sullivan, Yang Sai, Chen Chen,