| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378663 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
The sulfamic acid phosphotyrosine mimetic was coupled with a previously known malonate template to obtain highly selective and potent inhibitors of HPTPβ. Potentially hydrolyzable malonate ester functionalities were replaced with 1,2,4-oxadiazoles without a significant effect on HPTPβ potency.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kande K.D. Amarasinghe, Artem G. Evidokimov, Kevin Xu, Cynthia M. Clark, Matthew B. Maier, Anil Srivastava, Anny-Odile Colson, Gina S. Gerwe, George E. Stake, Brian W. Howard, Matthew E. Pokross, Jeffrey L. Gray, Kevin G. Peters,