| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378712 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Several analogues of UK-2A, a novel antifungal antibiotic isolated from Streptomyces sp. 517-02, were semi-synthesized for structure–activity studies. In vitro antifungal activities of these compounds against Saccharomyces cerevisiae IFO 0203 were evaluated by the conventional paper disk method. Several derivatives exhibited growth inhibitory activity similar to UK-2A.
Graphical abstractIn vitro antifungal activities of several semi-synthesized analogues of UK-2A, a novel antifungal antibiotic isolated from Streptomyces sp. 517-02 against Saccharomyces cerevisiae IFO 0203 were evaluated by the conventional paper disk method. Several derivatives exhibited growth inhibitory activity similar to UK-2A.Figure optionsDownload full-size imageDownload as PowerPoint slide
