| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378713 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Abstract
Several β-lactam nucleoside chimeras 1 (cis) and 2 (trans) were synthesized from the corresponding N-propargyl nucleobases via Kinugasa reaction in moderate yields. Initial screening for antibacterial activity against ampicillin sensitive E. coli showed weak activity for the uracil-β-lactam chimera.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Amit Basak, Runa Pal,