The role of QSAR in dopamine interactions

Dopamine receptor blockers have been used for the treatment of schizophrenia for many years. We have developed 22 quantitative structure activity relationships (QSAR) for different sets of compounds to understand chemical–biological interactions governing their activities toward dopamine receptors.

Graphical abstractQuantitative structure–activity relationships have been performed for different sets of compounds with respect to their activities toward dopamine receptors.Figure optionsDownload full-size imageDownload as PowerPoint slide