Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1378765 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Various 6-aryl-3-cyano/methoxycarbonyl-4-methylsulfanyl-2H-pyran-2-ones have been synthesized as a potential substitute of 2,4-thiazolidinedione head group to express potent PPAR-γ transactivation response. Some of the screened compounds have shown promising PPAR-γ agonistic activity.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ashoke Sharon, Ramendra Pratap, Rit Vatsyayan, Prakas R. Maulik, Uma Roy, Atul Goel, Vishnu Ji Ram,