| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378782 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
A series of cyclohexylpiperazines was synthesized as potent and selective antagonists of the human MC4 receptor. Compound 14t displayed binding affinity (Ki) of 4.2 and 1100 nM at MC4R and MC3R, respectively.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Joseph A. Tran, Joseph Pontillo, Melissa Arellano, Beth A. Fleck, Fabio C. Tucci, Dragan Marinkovic, Caroline W. Chen, John Saunders, Alan C. Foster, Chen Chen,