| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378851 | Bioorganic & Medicinal Chemistry Letters | 2006 | 5 Pages |
Abstract
Potent inhibitors of the human PDE IV enzyme are described. Substituted 8-arylquinoline analogs bearing nitrogen-linked side chain were identified as potent inhibitors based on the SAR described herein.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Patrick Lacombe, Denis Deschênes, Daniel Dubé, Laurence Dubé, Michel Gallant, Dwight Macdonald, Antony Mastracchio, Hélène Perrier, Stella Charleson, Zheng Huang, France Laliberté, Susana Liu, Joseph A. Mancini, Paul Masson, Myriam Salem,