Discovery of bitriazolyl compounds as novel antiviral candidates for combating the tobacco mosaic virus

Bitriazolyl compounds were synthesized and their activity against tobacco mosaic virus was assessed. Two of them showed promising antiviral activity and were more potent than the reference compounds. Moreover, these compounds are predicted not to be carcinogenic or mutagenic based on the prediction systems. Therefore, the bitriazolyl compounds may provide interesting new leads or scaffolds for use in further attempts to screen novel antiviral candidates.

Graphical abstractBitriazolyl compounds have been discovered to show promising antiviral activity against tobacco mosaic virus and may constitute interesting leads for the development of new antiviral candidates.Figure optionsDownload full-size imageDownload as PowerPoint slide