| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1378917 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
Using structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.
Graphical abstractUsing structure-based design, a new class of inhibitors of protein tyrosine phosphatase-1B (PTP1B) has been identified, which incorporate the 1,2,5-thiadiazolidin-3-one-1,1-dioxide template.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Emma Black, Jason Breed, Alexander L. Breeze, Kevin Embrey, Robert Garcia, Thomas W. Gero, Linda Godfrey, Peter W. Kenny, Andrew D. Morley, Claire A. Minshull, Andrew D. Pannifer, Jon Read, Amanda Rees, Daniel J. Russell, Dorin Toader, Julie Tucker,