| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1379255 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
Chemical synthesis of complex-type glycans 1 and 2 derived from eggs of parasitic helminths, Schistosoma mansoni and Schistosoma japonicum, is described. These branched sugar chains were synthesized regio- and stereoselectively by using β-mannosylation, desilylation under high pressure, and glycosylation in frozen solvent as key transformations.
Graphical abstractSynthesis of branched complex-type glycans derived from helminth glycoproteins is described.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jun Nakano, Hiromichi Ohta, Yukishige Ito,