| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1379280 | Bioorganic & Medicinal Chemistry Letters | 2006 | 6 Pages |
Abstract
A series of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives has been synthesized. Several functional groups were identified as the optimal C3-substituents, and the best compounds in this series possess potent in vitro antibacterial activity against erythromycin-susceptible and erythromycin-resistant bacteria.
Graphical abstractA series of 3-O-acyl-6-O-carbamoyl erythromycin A derivatives has been synthesized. The best compounds in this series possess potent in vitro antibacterial activity against erythromycin-susceptible and erythromycin-resistant bacteria.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bin Zhu, Brett A. Marinelli, Darren Abbanat, Barbara D. Foleno, Todd C. Henninger, Karen Bush, Mark J. Macielag,