| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1379581 | Bioorganic & Medicinal Chemistry Letters | 2005 | 7 Pages |
Abstract
Substitution of five-membered heterocycles on to the 'piperazinyl-phenyl-oxazolidinone' core structure led to the identification of ranbezolid as a clinical candidate. Further replacement of piperazine ring with other diamino-heterocycles led to compounds with potent antibacterial activity.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Biswajit Das, Sonali Rudra, Ajay Yadav, Abhijit Ray, A.V.S. Raja Rao, A.S.S.V. Srinivas, Ajay Soni, Suman Saini, Shalini Shukla, Manisha Pandya, Pragya Bhateja, Sunita Malhotra, Tarun Mathur, S.K. Arora, Ashok Rattan, Anita Mehta,