Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1379584 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
The hepatitis C virus proteinase inhibitor 4-methyl-1-(phenylmethyl)-2,6-pyridinedione 1 undergoes a novel autoxidation process, on silica gel, leading to the dimer 2 as the major product, a relatively more potent inhibitor of the enzyme.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Frank Bennett, Yi-Tsung Liu, Anil K. Saksena, Ashok Arasappan, Nancy Butkiewicz, Bimalendu Dasmahapatra, John S. Pichardo, F. George Njoroge, Naginbhai M. Patel, Yuhua Huang, Xiaozheng Yang,