Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1379604 | Bioorganic & Medicinal Chemistry Letters | 2005 | 4 Pages |
Abstract
Several efficient synthetic routes for 2-, 4-, and 6-aryl-1,2,4-triazine-3,5-diones were developed. Derivatives were synthesized and studied as gonadotropin-releasing hormone antagonists in an effort to understand structure–activity relationships of the monocyclic compounds.
Graphical abstractSeveral efficient synthetic routes for 2-, 4-, and 6-aryl-1,2,4-triazine-3,5-diones were developed. Derivatives were synthesized and studied as gonadotropin-releasing hormone antagonists in an effort to understand structure–activity relationships of the monocyclic compounds.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
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Authors
Joseph Pontillo, Zhiqiang Guo, Dongpei Wu, R. Scott Struthers, Chen Chen,