| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1379716 | Bioorganic & Medicinal Chemistry Letters | 2005 | 5 Pages |
Abstract
4,5-Disubstituted cis-pyrrolidinones were investigated as inhibitors of type II 17β-hydroxysteroid dehydrogenase (17β-HSD). Early structure–activity relationship patterns for this class of compounds are discussed.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David Gunn, Christiana Akuche, Jeremy Baryza, Marie-Louise Blue, Catherine Brennan, Ann-Marie Campbell, Soongyu Choi, James Cook, Patricia Conrad, Brian Dixon, Jacques Dumas, Paul Ehrlich, Todd Gane, Ted Joe, Jeffrey Johnson, Jerold Jordan,