| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1382469 | Bioorganic & Medicinal Chemistry Letters | 2010 | 6 Pages |
Abstract
The synthesis and CETP inhibitory activity of compounds related to wiedendiols (1a, 1b) are reported. It is proposed that a two point pharmacophore with a catechol group and a large hydrophobic anchor is necessary for activity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Samuel Chackalamannil, Yan Xia, Yuguang Wang, Hsingan Tsai, Michael Czarniecki, Suke Wang, Anthony Clemmons, Ho-Sam Ahn, George Boykow,