| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1382470 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
In order to study the structure-activity relationships, several dioxolane pyrimidine nucleosides have been synthesized and their anti-HBV activities have been evaluated in 2.2.15 cells. From the study it was found that 5-fluoro-cytosine derivatives exhibited the most potent anti-HBV activity.
Several dioxolane cytosine nucleosides have been synthesized and their anti-HBV activities have been evaluated in 2.2.15 cells. From the study it was found that 5-fluoro-cytosine derivative exhibited potent anti-HBV activity.Figure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Migyoung Lee, Chung K. Chu, S. Balakrishna Pai, Yong-Lian Zhu, Yung-Chi Cheng, Moon Woo Chun, Won Keun Chung,