Microfluidic devices fabricated using stereolithography for preparation of monodisperse double emulsions

•Three-dimensional microfluidic devices were fabricated using stereolithography.•The devices generate monodisperse O/W/O and W/O/W double emulsions.•The sizes and numbers of droplets were precisely controlled.•Monodisperse double emulsions with three different inner droplets were prepared.

We demonstrate the fabrication of microfluidic devices with three-dimensional flow channels using stereolithography. The fabricated devices can generate monodisperse double emulsions and enable precision control of the sizes and number of encapsulated droplets. In addition, monodisperse double emulsions with three different inner droplets can be generated in a device with three different inner channels. Since devices fabricated using stereolithography can be easily extended to generate higher-order multiple emulsions with more compartments, this method is potentially useful for a broad range of applications in drug delivery, food, cosmetics, and materials science applications.

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