High glucose yields from the hydrolysis of cellulose dissolved in ionic liquids

Here we show a method to hydrolyze cellulose selectively to glucose and cellobiose, sugars that can be easily fermented. Selecting an ideal ionic liquid ([EMIM]Cl), optimizing the dissolution time/temperature (15 min, 408 K) and the reaction procedure (addition of water during the reaction time) led to a very high selectivity to glucose + cellobiose (99.6%).

Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► We show a very efficient chemical hydrolysis of cellulose in ionic liquid. ► The progressive addition of water avoids the formation of dehydration products. ► The dissolution conditions play a key role in the final yield to fermentable sugars. ► This procedure yields very high selectivity to glucose + cellobiose (99.6%).