| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1942596 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2011 | 6 Pages |
Abstract
⺠Effects of four mutations identified in prostate cancer patients were characterized at a molecular-functional level. ⺠The data indicate that the mutations destabilize the enzyme structure thereby influencing proton gating. ⺠The bacterial R. sphaeroides cytochrome c oxidase was used as a model to investigate effects of disease-related mutations in the enzyme.
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Authors
Ida Namslauer, Marina S. Dietz, Peter Brzezinski,