Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1943662 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2006 | 7 Pages |
Abstract
The steps in the mechanism of proton transport in bacteriorhodopsin include examples for most kinds of proton transfer reactions that might occur in a transmembrane pump: proton transfer via a bridging water molecule, coupled protonation/deprotonation of two buried groups separated by a considerable distance, long-range proton migration over a hydrogen-bonded aqueous chain, and capture as well as release of protons at the membrane–water interface. The conceptual and technical advantages of this system have allowed close examination of many of these model reactions, some at an atomic level.
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Authors
Janos K. Lanyi,